Design & Development of Laboratory Test Kits for IVD
Elevated prognosis of autoimmune childhood-onset Japanese sort 1 diabetes utilizing a brand new GADAb ELISA package
Elevated prognosis of autoimmune childhood-onset Japanese sort 1 diabetes utilizing a brand new GADAb ELISApackage, in contrast with a beforehand used GADAb RIA package.
We in contrast the outcomes of testing for glutamic acid decarboxylase antibodies (GADAb) utilizing a radioimmunoassay (RIA) and an enzyme-linked immunosorbent assay (ELISA) in topics with childhood-onset sort 1 diabetes mellitus (T1D).Serum specimens had been collected from 1024 Japanese instances (426 boys and 598 ladies) in 2013. The median age at prognosis was 7 years (0-18 years). The blood specimens had been obtained at a median age of 13 years (2-22 years).
Among the many 628 topics whose serum specimens had been collected inside 5 years after prognosis, the speed of GADAb positivity was 47.9% utilizing RIA and 69.4% utilizing ELISA. The themes had been divided into 4 teams in response to their RIA and ELISA outcomes for GADAb as follows: Gr I (RIA+/ELISA+), Gr II (RIA+/ELISA-), Gr III (RIA-/ELISA+), and Gr IV (RIA-/ELISA-). The medical and genetic traits of Gr I and Gr III had been fairly comparable when it comes to age at prognosis, male/feminine ratio, comparatively excessive constructive charges for each IA-2Ab and ZnT8Ab, and HLA genotype.
Gr II contained solely 5 sufferers and was characterised by a youthful age at prognosis, low constructive charges for each IA-2Ab and ZnT8Ab, and a novel HLA genotype. If the constructive charges of both IA-2Ab or ZnT8Ab or each had been added to the GADAb outcomes utilizing RIA, the proportion of autoimmune T1D elevated from 47.9% to 78.5%.The prognosis of autoimmune childhood-onset Japanese T1D elevated when GADAb outcomes had been obtained utilizing a brand new ELISA technique, in contrast with a beforehand utilized RIA technique.
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Human Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody (IgG) in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Qualitativeindirect ELISA kit for measuring Human Hsp60 antibody(IgG) in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody (IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 antibody(IgM) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human Hsp60 IgA antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Goat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Canine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rabbit Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Porcine Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Mouse Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Rat Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: A sandwich ELISA for quantitative measurement of Monkey Helicobacter pylori Hsp60 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.
Description: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes, and the regulation of protein folding. The mitochondrial and cytosolic localization of HSP60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker for T cell recognition, as well as being involved in a danger signal cascade immune response. HSP60 has been shown to influence apoptosis in tumor cells, and changes in its expression level may serve as a biomarker, as down-regulated HSP60 expression indicates a poor prognosis as well as a risk of tumor infiltration development, especially with regard to urothelial carcinomas. In ovarian cancer, decreased expression of HSP60 correlates with aggressive tumor types, while overexpression is correlated with a better patient prognosis.
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.
Description: This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60. The antibody's epitope is localized between amino acids 383-447 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK1 antibody, unlike LK2 antibody, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
Description: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]
Description: HSP60 has been implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. [UniProt]
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (Hsp60). Its epitope is localized between amino acids 383-447 of human Hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial Hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (Hsp60). Its epitope is localized between amino acids 383-447 of human Hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial Hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (Hsp60). Its epitope is localized between amino acids 383-447 of human Hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial Hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (Hsp60). Its epitope is localized between amino acids 383-447 of human Hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial Hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Description: Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
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Comparability of 4 commercially obtainable ELISAkits for prognosis of Fasciola hepatica in Irish cattle.
Fasciola hepatica is a liver parasite of mammals and it leads to poor welfare outcomes and financial losses in ruminants. Whereas faecal egg depend is the check mostly used for prognosis, it doesn’t point out presence of migrating immature levels. Serological strategies enhance sensitivity in any respect levels of the liver fluke an infection.
The purpose of this examine was to check 4 commercially obtainable ELISA checks for the prognosis of F. hepatica. For this function, we examined three pattern varieties; (i) recognized F. hepatica standing sera from an experimental an infection for the comparability of sensitivities and specificities, (ii) sera from pre- and post-flukicide-treated (albendazole, closantel, nitroxynil and triclabendazole) beef cattle to distinction the variations of seropositivity earlier than and after remedy, and (iii) bulk tank milk samples from dairy herds sampled throughout excessive and low F.
hepatica publicity durations for assessing differences due to the season with the 4 checks obtainable. Samples had been examined utilizing ELISA kits equipped by 4 producers (Ildana Biotech, IDEXX, Svanova, and Bio-X). Samples had been analysed concurrently and in duplicate.Within the management inhabitants Ildana, IDEXX and Bio-X introduced 100% sensitivity (Se) and specificity (Sp), Svanovir introduced a Se of 59% and a Sp of 96%. In flukicide-treated beef cattle, kits highlighted lowering antibody ranges 90 days post-treatment in variable levels. Lastly, bulk milk confirmed a big lower in ELISA worth between excessive and low fluke publicity durations with all checks studied.Se and Sp discovered within the current examine, verify that Ildana, IDEXX and Bio-X are correct for the detection of F. hepatica publicity in Irish cattle.
Svanovir Se and Sp on this inhabitants, point out {that a} bigger examine is critical to verify this check attribute in Irish herds. In post-treatment use, Bio-X confirmed a constant and vital lower of ELISA worth in all teams handled, denoting to be a dependable software for assessing remedy impact at 90 days post-treatment. Lastly, all checks confirmed to be a dependable software for the F. hepatica monitoring of excessive and low publicity seasons, utilizing bulk tank milk samples.
Comparative analysis of two business ELISAkits for detection of antibodies in opposition to Akabane virus in cattle serum.
Akabane illness (AD), a barrier to worldwide commerce for endemic areas with far financial influence on the nations, is attributable to Akabane virus (AKAV). Business enzyme-linked immunosorbent assay (ELISA) is a generally used diagnostic method for AKAV an infection, together with the IDEXX and IDVET ELISA kits. Nonetheless, the comparative analysis of the IDEXX and IDVET ELISA kits has not been revealed.
The thing of this examine was to guage the check efficiency of the 2 business ELISA kits in detecting serum anti-AKAV antibodies in cattle.With virus neutralization check (VNT) because the “relative gold normal”, the diagnostic sensitivity (DSe) was 80.39% (123/153) and 93.46% (143/153) for the IDEXX and IDVET ELISA package, when suspect samples had been included.
The diagnostic specificity (DSp) for the IDEXX and IDVET ELISA package was 93.48% (502/537) and 82.31% (442/537), respectively. Each of the examined ELISA kits could possibly be utilized to detect antibodies in opposition to AKAV in cattle serum. The IDVET ELISA package had a better DSe. The IDEXX ELISA package possessed the upper DSp. These outcomes have essential implications if the kits are used to display screen herds or particular person cattle in surveillance applications, or at border crossings for import-export inspection and quarantine.
Description: Quantitativesandwich ELISA kit for measuring Rat heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Quantitativesandwich ELISA kit for measuring Mouse heme oxygenase 1, HO-1 in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Enzyme-linked immunosorbent assay kit for quantification of Human HO-1/HMOX1 in samples from serum, plasma, tissue homogenates and other biological fluids.
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Rat heme oxygenase 1, HO-1 in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Mouse heme oxygenase 1, HO-1 in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Description: Quantitativesandwich ELISA kit for measuring Human heme oxygenase 2, HO-2 in samples from serum, plasma, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Description: Heme Oxygenase 1 (HO-1) is an enzyme in endoplasmic reticulum that belongs to the heme oxygenase family. HO-1 cleaves the heme ring at the alpha methene bridge to form Biliverdin. Biliverdin is subsequently converted to Bilirubin by Biliverdin reductase. In physiological state, the highest activity of HO-1 is found in the spleen, where senescent erythrocytes are sequestrated and destroyed. HO-1 activity is highly inducible by its substrate heme and by various non-heme substances such as heavy metals, bromobenzene, endotoxin, oxidizing agents and UVA. HO-1 is involved in the regulation of cardiovascular function and response to a variety of stressors. Defects in HO-1 are the cause of Heme Oxygenase 1 deficiency, resulting in marked erythrocyte fragmentation and intravascular hemolysis, coagulation abnormalities, endothelial damage, and iron deposition in renal and hepatic tissues.
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.
Description: His tagged recombinant rat HO-1 Protein expressed in E. coli for WB, SDS-PAGE. The biological activity of this protein has not yet been tested.
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, GE601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
PinPoint-HR System for Platform Cell Line Generation & Retargeting of AAVS1 Safe Harbor Locus (includes PIN410A-1, CAS601A-1, PIN200A-1, PIN510A-1, & PIN600A-1)
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis.
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis.
Description: HO-3867 is a novel curcumin analog and a selective inhibitor of STAT3. [1]STAT3 (signal transducer and activator of transcription 3) belongs to the STAT protein family. It mediates various gene expressions for numerous cellular functions, including cell growth, division and apoptosis.
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HMOX1 / HO-1 . This antibody is tested and proven to work in the following applications:
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is unconjugated.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Alkaline Phosphatase.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to APC .
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to APC/Cy7.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Biotin.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Dylight 350.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Dylight 405.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Dylight 488.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Dylight 594.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Dylight 633.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to FITC.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to HRP.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to PE/ATTO 594.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to PerCP.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to RPE .
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is conjugated to Streptavidin.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat. The antibody is produced in rabbit after immunization with Rat Rat native full-length HO-1 purified from liver tissue. The Antibody is tested and validated for WB, IHC, IP assays with the following recommended dilutions: WB (1:400), IHC (1:1000), IP (1:100). This HO-1 antibody is unconjugated.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is unconjugated.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is unconjugated.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 390.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 488.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 565.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 594.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 633.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 655.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 680.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to ATTO 700.
Description: A polyclonal antibody for HO-1 from Human | Mouse | Rat | Dog. The antibody is produced in rabbit after immunization with human heme-oxygenase (HO-1) synthetic multiple antigenic peptide. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000), ICC/IF (1:100). This HO-1 antibody is conjugated to Alkaline Phosphatase.
