Histoclear 11 1 gall

Histoclear 11 1 gall 

To Order Contact us: lieven@wlsolutions.be

Human Gall Bladder Slide (Benign) (5 slides/pk)
HTS-12403	1 pk	EUR 286

Human Gall Bladder Slide (Abnormal) (5 slides/pk)
HTS-12417	1 pk	EUR 286

Recombinant Murine IL-11 Protein
PROTP47873-1	10ug	EUR 317
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

5?-dihydro-11-keto Testosterone
C4317-1	1 mg	EUR 181
Description: 5?-dihydro-11-keto Testosterone (11KDHT) is a full androgen receptor agonist comparable to dihydrotestosterone (DHT) [1][2][3].

Biotin-11-dUTP, lyophilized powder (Biotin-11-2'-deoxyuridine-5'-triphosphate, tetralithium salt
40029-1	50uG	EUR 299
Description: Minimum order quantity: 1 unit of 50uG

france bridge 11 cm
EHCA1200-BR11B15-1	ea	EUR 60

[Sar9,Met(O2)11]-Substance P
B6623-1	1 mg	EUR 195

Human Kallikrein-11 (KLK11) AssayMax ELISA Kit
EK1110-1	96 Well Plate	EUR 477

Neurotensin (1-11)
5-01620	4 x 5mg	Ask for price

Neurotensin (1-11)
H-4455.0005	5.0mg	EUR 151
Description: Sum Formula: C66H99N19O18; CAS# [74032-89-6]

Neurotensin (1-11)
H-4455.0025	25.0mg	EUR 515
Description: Sum Formula: C66H99N19O18; CAS# [74032-89-6]

Human Factor XI (Factor 11) AssayMax ELISA Kit
EF1011-1	96 Well Plate	EUR 396

Adrenomedullin (Adrenomedullin (ADM/AM, 11-50) (rat)
SP-100047-1	1 mg	EUR 529

β-amyloid (1-11)
HY-P1510	5mg	EUR 211

[Ala4] - MBP (1 - 11)
5-00024	4 x 5mg	Ask for price

[Tyr4] - MBP (1 - 11)
5-00354	4 x 5mg	Ask for price

beta-Amyloid (1-11)
5-00416	4 x 5mg	Ask for price

ANP (1-11), rat
5-00702	4 x 5mg	Ask for price

Endothelin-1 (11-21)
5-01101	4 x 1mg	Ask for price

MBP (1-11), human
5-01518	4 x 5mg	Ask for price

MBP (1 - 11), mouse
5-01519	4 x 5mg	Ask for price

MBP (1-11) Peptide
20-abx265049	EUR 495.00 EUR 815.00 EUR 356.00	10 mg 25 mg 5 mg

MBP (1 11) Peptide
20-abx265384	EUR 495.00 EUR 815.00 EUR 356.00	10 mg 25 mg 5 mg

ANP (1-11) Peptide
20-abx265569	EUR 523.00 EUR 272.00 EUR 356.00	10 mg 2 mg 5 mg

Neurotensin (1-11) Peptide
20-abx265902	EUR 370.00 EUR 523.00 EUR 286.00	10 mg 25 mg 5 mg

C.I.Basic Violet 11:1
abx180051-25g	25 g	EUR 342

11-Bromo-1-undecene
20-abx181519	EUR 398.00 EUR 244.00	25 g 5 g

Beta-Amyloid (1-11)
A1002-10	10 mg	EUR 311
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein.

Beta-Amyloid (1-11)
A1002-25	25 mg	EUR 415
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein.

Beta-Amyloid (1-11)
A1002-5	5 mg	EUR 206
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein.

ANP (1-11), rat
A1009-10	10 mg	EUR 224
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation.

ANP (1-11), rat
A1009-25	25 mg	EUR 293
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation.

ANP (1-11), rat
A1009-5	5 mg	EUR 154
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation.

Endothelin-1 (11-21)
H-1658.0001	1.0mg	EUR 212
Description: Sum Formula: C68H92N14O15S2; CAS# [144602-02-8] net

Endothelin-1 (11-21)
H-1658.0005	5.0mg	EUR 756
Description: Sum Formula: C68H92N14O15S2; CAS# [144602-02-8] net

GDF11 Human, Growth and Differentiation factor 11 Human Recombinant Protein, His Tag
PROTO95390-1	Regular: 20ug	EUR 317
Description: GDF11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids (299-407a.a) and having a molecular mass of 14.8kDa. GDF11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Rabbit Anti-Human Glucose 11 (Glut-11) antiserum # 1
GT111-S	100 ul	EUR 457

Mucin-1 / MUC-1 Recombinant Protein
11-543	0.1 mg	EUR 490.25
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.

IL-1 Rrp2 / IL-1 R6 Recombinant Protein
11-170	0.1 mg	EUR 542.75
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.

Mucin-1 / MUC-1 (1036-1155) Recombinant Protein
11-281	0.1 mg	EUR 595.25
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.

Mucin-1 / MUC-1 (890-1158) Recombinant Protein
11-283	0.1 mg	EUR 542.75
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.

IL-1 Rrp2 / IL-1 R6 Recombinant Protein
11-437	0.1 mg	EUR 542.75
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.

IL-1 Rrp2 / IL-1 R6 Recombinant Protein
11-448	0.1 mg	EUR 542.75
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.

Endothelin-1 (11-21) (AA: Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
SP-89900-1	1 mg	EUR 164

Tax9, HTLV - 1 (11 - 19)
5-02003	4 x 5mg	Ask for price

Dynorphin A (1-11), porcine
5-01059	4 x 5mg	Ask for price

Dynorphin A (1-11) Peptide
20-abx265496	EUR 467.00 EUR 759.00 EUR 342.00	10 mg 25 mg 5 mg

beta Amyloid (1-11) Peptide
20-abx266241	EUR 467.00 EUR 759.00 EUR 342.00	10 mg 25 mg 5 mg

[Ala4] MBP (1 11) Peptide
20-abx266287	EUR 495.00 EUR 815.00 EUR 356.00	10 mg 25 mg 5 mg

[Tyr4] MBP (1 11) Peptide
20-abx266361	EUR 523.00 EUR 871.00 EUR 384.00	10 mg 25 mg 5 mg

Amyloid b-Protein (1-11)
H-2956.0001	1.0mg	EUR 113
Description: Sum Formula: C56H76N16O22; CAS# [190436-05-6] net

Amyloid b-Protein (1-11)
H-2956.0005	5.0mg	EUR 274
Description: Sum Formula: C56H76N16O22; CAS# [190436-05-6] net

Dynorphin A (1-11) amide
H-5068.0005	5.0mg	EUR 683
Description: Sum Formula: C63H104N22O12; CAS# [79985-48-1] net

Dynorphin A (1-11) amide
H-5068.0025	25.0mg	EUR 2642
Description: Sum Formula: C63H104N22O12; CAS# [79985-48-1] net

HTLV-1 Tax (11-19)
H-6096.0001	1.0mg	EUR 115
Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net

HTLV-1 Tax (11-19)
H-6096.0005	5.0mg	EUR 368
Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net

Amino-11-ddUTP, 1 umol
15040	1 umol	EUR 415

Amino-11-dUTP, 1 umol
16040	1 umol	EUR 97

Human Glucose Transp. 11 (Glut-11) Control/blocking peptide # 1
GT111-P	100 ug	EUR 164

Calpain 11 (Calpain 11) Antibody
20-abx121925	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Calpain 11 (Calpain 11) Antibody
20-abx111329	EUR 732.00 EUR 398.00	150 ul 50 ul

11-Hydroxyprogesterone (11-OHP) Antibody
20-abx102405	EUR 425.00 EUR 133.00 EUR 1177.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug

Kallikrein 11 (Kallikrein 11) Antibody
20-abx007794	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Kallikrein 11 (Kallikrein 11) Antibody
20-abx008292	EUR 300.00 EUR 439.00 EUR 189.00	100 ul 200 ul 30 ul

Syntaxin 11 (Syntaxin 11) Antibody
abx431886-200ul	200 ul	EUR 384

Calpain 11 (Calpain 11) Antibody
abx231212-100ug	100 ug	EUR 481

Syntaxin 11 (Syntaxin 11) Antibody
abx238445-100ug	100 ug	EUR 509

Kallikrein 11 (Kallikrein 11) Antibody
abx234457-100ug	100 ug	EUR 481

IL-11, Interleukin-11, human
RC212-22	2ug	EUR 104.38

IL-1 Rrp2 / IL-1 R6 (C154S, C262S) Recombinant Protein
11-120	0.1 mg	EUR 542.75
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.

Kremen-1 Recombinant Protein
11-155	0.1 mg	EUR 684.5
Description: Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD).

Syndecan-1 Recombinant Protein
11-168	0.1 mg	EUR 595.25
Description: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

Neurotensin (1-11) [pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-OH; MW 1446.66]
SP-55373-1	1 mg	EUR 141

Mouse 11-beta hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) Control/blocking peptide
BHSD11-P	100 ug	EUR 164

Rabbit Anti-Mouse 11-beta hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) antiserum
BHSD11-S	100 ul	EUR 457

LIV-1 / SLC39A6 Recombinant Protein
11-143	0.1 mg	EUR 684.5
Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

LIV-1 / SLC39A6 Recombinant Protein
11-144	0.1 mg	EUR 684.5
Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines.

Biotinylated Syndecan-1 Recombinant Protein
11-169	0.025 mg	EUR 595.25
Description: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity.

IFN-alpha 1 Recombinant Protein
11-192	0.1 mg	EUR 595.25
Description: Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.

IFN-alpha 1 Recombinant Protein
11-193	0.1 mg	EUR 595.25
Description: Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.

Siglec-1 / CD169 Recombinant Protein
11-194	0.1 mg	EUR 595.25
Description: Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells.

NRG1 Beta 1 Recombinant Protein
11-224	0.1 mg	EUR 542.75
Description: NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

Iba1 / AIF-1 Recombinant Protein
11-239	0.1 mg	EUR 516.5
Description: Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

PSGL-1 / CD162 Recombinant Protein
11-244	0.1 mg	EUR 595.25
Description: P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG.

Glypican 1 / GPC1 Recombinant Protein
11-321	0.1 mg	EUR 595.25
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Glypican 1 / GPC1 Recombinant Protein
11-327	0.1 mg	EUR 595.25
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

Glypican 1 / GPC1 Recombinant Protein
11-328	0.1 mg	EUR 595.25
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.

CD28H / IGPR-1 Recombinant Protein
11-383	0.1 mg	EUR 595.25
Description: CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

PD-1 / PDCD1 Recombinant Protein
11-403	0.1 mg	EUR 542.75
Description: Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.

DNAM-1 / CD226 Recombinant Protein
11-431	0.1 mg	EUR 595.25
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

Histoclear 11 1 gall