Histoclear 11 1 gall
To Order Contact us: lieven@wlsolutions.be
Human Gall Bladder Slide (Benign) (5 slides/pk) |
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HTS-12403 | 1 pk | EUR 286 |
Human Gall Bladder Slide (Abnormal) (5 slides/pk) |
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HTS-12417 | 1 pk | EUR 286 |
Recombinant Murine IL-11 Protein |
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PROTP47873-1 | 10ug | EUR 317 |
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues. |
5?-dihydro-11-keto Testosterone |
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C4317-1 | 1 mg | EUR 181 |
Description: 5?-dihydro-11-keto Testosterone (11KDHT) is a full androgen receptor agonist comparable to dihydrotestosterone (DHT) [1][2][3]. |
Biotin-11-dUTP, lyophilized powder (Biotin-11-2'-deoxyuridine-5'-triphosphate, tetralithium salt |
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40029-1 | 50uG | EUR 299 |
Description: Minimum order quantity: 1 unit of 50uG |
france bridge 11 cm |
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EHCA1200-BR11B15-1 | ea | EUR 60 |
[Sar9,Met(O2)11]-Substance P |
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B6623-1 | 1 mg | EUR 195 |
Human Kallikrein-11 (KLK11) AssayMax ELISA Kit |
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EK1110-1 | 96 Well Plate | EUR 477 |
Neurotensin (1-11) |
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5-01620 | 4 x 5mg | Ask for price |
Neurotensin (1-11) |
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H-4455.0005 | 5.0mg | EUR 151 |
Description: Sum Formula: C66H99N19O18; CAS# [74032-89-6] |
Neurotensin (1-11) |
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H-4455.0025 | 25.0mg | EUR 515 |
Description: Sum Formula: C66H99N19O18; CAS# [74032-89-6] |
Human Factor XI (Factor 11) AssayMax ELISA Kit |
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EF1011-1 | 96 Well Plate | EUR 396 |
Adrenomedullin (Adrenomedullin (ADM/AM, 11-50) (rat) |
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SP-100047-1 | 1 mg | EUR 529 |
β-amyloid (1-11) |
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HY-P1510 | 5mg | EUR 211 |
[Ala4] - MBP (1 - 11) |
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5-00024 | 4 x 5mg | Ask for price |
[Tyr4] - MBP (1 - 11) |
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5-00354 | 4 x 5mg | Ask for price |
beta-Amyloid (1-11) |
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5-00416 | 4 x 5mg | Ask for price |
ANP (1-11), rat |
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5-00702 | 4 x 5mg | Ask for price |
Endothelin-1 (11-21) |
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5-01101 | 4 x 1mg | Ask for price |
MBP (1-11), human |
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5-01518 | 4 x 5mg | Ask for price |
MBP (1 - 11), mouse |
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5-01519 | 4 x 5mg | Ask for price |
MBP (1-11) Peptide |
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20-abx265049 |
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MBP (1 11) Peptide |
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20-abx265384 |
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ANP (1-11) Peptide |
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20-abx265569 |
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Neurotensin (1-11) Peptide |
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20-abx265902 |
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C.I.Basic Violet 11:1 |
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abx180051-25g | 25 g | EUR 342 |
11-Bromo-1-undecene |
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20-abx181519 |
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Beta-Amyloid (1-11) |
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A1002-10 | 10 mg | EUR 311 |
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein. |
Beta-Amyloid (1-11) |
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A1002-25 | 25 mg | EUR 415 |
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein. |
Beta-Amyloid (1-11) |
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A1002-5 | 5 mg | EUR 206 |
Description: Beta-amyloid (1-11) (Abeta or A?) (C56H76N16O22) is a peptide with the sequence H-{Asp}{Ala}{Glu}{Phe}{Arg}{His}{Asp}{Ser}{Gly}{Tyr}{Glu}-OH,which is processed from the Amyloid precursor protein. |
ANP (1-11), rat |
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A1009-10 | 10 mg | EUR 224 |
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation. |
ANP (1-11), rat |
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A1009-25 | 25 mg | EUR 293 |
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation. |
ANP (1-11), rat |
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A1009-5 | 5 mg | EUR 154 |
Description: Atrial Natriuretic Peptide (ANP) (C49H84N20O15S) has the sequence of H-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-OH, is a 28 amino acid peptide that is synthesized, stored, and released by atrial myocytes in response to atrial distension, endothelin, and sympathetic stimulation. |
Endothelin-1 (11-21) |
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H-1658.0001 | 1.0mg | EUR 212 |
Description: Sum Formula: C68H92N14O15S2; CAS# [144602-02-8] net |
Endothelin-1 (11-21) |
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H-1658.0005 | 5.0mg | EUR 756 |
Description: Sum Formula: C68H92N14O15S2; CAS# [144602-02-8] net |
GDF11 Human, Growth and Differentiation factor 11 Human Recombinant Protein, His Tag |
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PROTO95390-1 | Regular: 20ug | EUR 317 |
Description: GDF11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids (299-407a.a) and having a molecular mass of 14.8kDa. GDF11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Rabbit Anti-Human Glucose 11 (Glut-11) antiserum # 1 |
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GT111-S | 100 ul | EUR 457 |
Mucin-1 / MUC-1 Recombinant Protein |
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11-543 | 0.1 mg | EUR 490.25 |
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. |
IL-1 Rrp2 / IL-1 R6 Recombinant Protein |
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11-170 | 0.1 mg | EUR 542.75 |
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
Mucin-1 / MUC-1 (1036-1155) Recombinant Protein |
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11-281 | 0.1 mg | EUR 595.25 |
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. |
Mucin-1 / MUC-1 (890-1158) Recombinant Protein |
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11-283 | 0.1 mg | EUR 542.75 |
Description: Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. |
IL-1 Rrp2 / IL-1 R6 Recombinant Protein |
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11-437 | 0.1 mg | EUR 542.75 |
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
IL-1 Rrp2 / IL-1 R6 Recombinant Protein |
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11-448 | 0.1 mg | EUR 542.75 |
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
Endothelin-1 (11-21) (AA: Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp |
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SP-89900-1 | 1 mg | EUR 164 |
Tax9, HTLV - 1 (11 - 19) |
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5-02003 | 4 x 5mg | Ask for price |
Dynorphin A (1-11), porcine |
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5-01059 | 4 x 5mg | Ask for price |
Dynorphin A (1-11) Peptide |
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20-abx265496 |
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beta Amyloid (1-11) Peptide |
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20-abx266241 |
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[Ala4] MBP (1 11) Peptide |
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20-abx266287 |
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[Tyr4] MBP (1 11) Peptide |
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20-abx266361 |
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Amyloid b-Protein (1-11) |
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H-2956.0001 | 1.0mg | EUR 113 |
Description: Sum Formula: C56H76N16O22; CAS# [190436-05-6] net |
Amyloid b-Protein (1-11) |
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H-2956.0005 | 5.0mg | EUR 274 |
Description: Sum Formula: C56H76N16O22; CAS# [190436-05-6] net |
Dynorphin A (1-11) amide |
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H-5068.0005 | 5.0mg | EUR 683 |
Description: Sum Formula: C63H104N22O12; CAS# [79985-48-1] net |
Dynorphin A (1-11) amide |
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H-5068.0025 | 25.0mg | EUR 2642 |
Description: Sum Formula: C63H104N22O12; CAS# [79985-48-1] net |
HTLV-1 Tax (11-19) |
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H-6096.0001 | 1.0mg | EUR 115 |
Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net |
HTLV-1 Tax (11-19) |
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H-6096.0005 | 5.0mg | EUR 368 |
Description: Sum Formula: C56H79N9O12; CAS# [141677-18-1] net |
Amino-11-ddUTP, 1 umol |
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15040 | 1 umol | EUR 415 |
Amino-11-dUTP, 1 umol |
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16040 | 1 umol | EUR 97 |
Human Glucose Transp. 11 (Glut-11) Control/blocking peptide # 1 |
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GT111-P | 100 ug | EUR 164 |
Calpain 11 (Calpain 11) Antibody |
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20-abx121925 |
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Calpain 11 (Calpain 11) Antibody |
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20-abx111329 |
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11-Hydroxyprogesterone (11-OHP) Antibody |
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20-abx102405 |
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Kallikrein 11 (Kallikrein 11) Antibody |
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20-abx007794 |
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Kallikrein 11 (Kallikrein 11) Antibody |
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20-abx008292 |
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Syntaxin 11 (Syntaxin 11) Antibody |
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abx431886-200ul | 200 ul | EUR 384 |
Calpain 11 (Calpain 11) Antibody |
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abx231212-100ug | 100 ug | EUR 481 |
Syntaxin 11 (Syntaxin 11) Antibody |
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abx238445-100ug | 100 ug | EUR 509 |
Kallikrein 11 (Kallikrein 11) Antibody |
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abx234457-100ug | 100 ug | EUR 481 |
IL-11, Interleukin-11, human |
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RC212-22 | 2ug | EUR 104.38 |
IL-1 Rrp2 / IL-1 R6 (C154S, C262S) Recombinant Protein |
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11-120 | 0.1 mg | EUR 542.75 |
Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
Kremen-1 Recombinant Protein |
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11-155 | 0.1 mg | EUR 684.5 |
Description: Kremens are high-affinity receptors for Dickkopf 1 (Dkk1) and regulate the Wnt/β-catenin signaling pathway by down-regulating the low-density lipoprotein receptor-related protein 6 (LRP6). Kremen1 is considered as one component of a membrane complex modulating canonical Wnt signalling through LRP6 in vertebrates. Additionally, KREMEN1 (KRM1) has also been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD). |
Syndecan-1 Recombinant Protein |
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11-168 | 0.1 mg | EUR 595.25 |
Description: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity. |
Neurotensin (1-11) [pGlu-Leu-Tyr-Glu-Asn-Lys-Pro-Arg-Arg-Pro-Tyr-OH; MW 1446.66] |
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SP-55373-1 | 1 mg | EUR 141 |
Mouse 11-beta hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) Control/blocking peptide |
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BHSD11-P | 100 ug | EUR 164 |
Rabbit Anti-Mouse 11-beta hydroxysteroid dehydrogenase-1 (11 beta-HSD-1) antiserum |
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BHSD11-S | 100 ul | EUR 457 |
LIV-1 / SLC39A6 Recombinant Protein |
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11-143 | 0.1 mg | EUR 684.5 |
Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines. |
LIV-1 / SLC39A6 Recombinant Protein |
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11-144 | 0.1 mg | EUR 684.5 |
Description: LIV-1 is also known as SLC39A6, ZIP-6 and Zinc transporter ZIP6. May act as a zinc-influx transporter. Highly expressed in the breast, prostate, placenta, kidney, pituitary and corpus callosum. Weakly expressed in heart and intestine. Also highly expressed in cells derived from an adenocarcinoma of the cervix and lung carcinoma. Up-regulated by estrogen in breast cancer cells lines. |
Biotinylated Syndecan-1 Recombinant Protein |
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11-169 | 0.025 mg | EUR 595.25 |
Description: Neuronal protein that plays several roles in synaptic activity such as regulation of synaptic vesicle trafficking and subsequent neurotransmitter release. Participates as a monomer in synaptic vesicle exocytosis by enhancing vesicle priming, fusion and dilation of exocytotic fusion pores. Mechanistically, acts by increasing local Ca2+ release from microdomains which is essential for the enhancement of ATP-induced exocytosis. Acts also as a molecular chaperone in its multimeric membrane-bound state, assisting in the folding of synaptic fusion components called SNAREs (Soluble NSF Attachment Protein REceptors) at presynaptic plasma membrane in conjunction with cysteine string protein-alpha/DNAJC5. This chaperone activity is important to sustain normal SNARE-complex assembly during aging. Plays also a role in the regulation of the dopamine neurotransmission by associating with the dopamine transporter (DAT1) and thereby modulating its activity. |
IFN-alpha 1 Recombinant Protein |
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11-192 | 0.1 mg | EUR 595.25 |
Description: Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes. |
IFN-alpha 1 Recombinant Protein |
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11-193 | 0.1 mg | EUR 595.25 |
Description: Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes. |
Siglec-1 / CD169 Recombinant Protein |
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11-194 | 0.1 mg | EUR 595.25 |
Description: Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. |
NRG1 Beta 1 Recombinant Protein |
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11-224 | 0.1 mg | EUR 542.75 |
Description: NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells. |
Iba1 / AIF-1 Recombinant Protein |
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11-239 | 0.1 mg | EUR 516.5 |
Description: Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. |
PSGL-1 / CD162 Recombinant Protein |
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11-244 | 0.1 mg | EUR 595.25 |
Description: P-selectin glycoprotein ligand 1 (PSGL-1) is also known as Selectin P ligand (SELPLG), CD antigen CD162. PSGL-1 is disulfide-linked homodimer which is the high affinitycounter-receptor for P-selectin on expressed on activated endothelial cells and platelets. PSGL-1 / SELPLG interacts with P-, E- and L-selectins, through their lectin/EGF domains, is required for promoting recruitment and rolling of leukocytes. These interactions require sialyl Lewis X glycan modification but there is a differing dependence for tyrosine sulfations. Dimerization appears not to be required for P-selectin/SELP binding. PSGL-1 can interact with SNX20, MSN and SYK. PSGL-1 / SELPLG mediate the activation of SYK by SELPLG. |
Glypican 1 / GPC1 Recombinant Protein |
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11-321 | 0.1 mg | EUR 595.25 |
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. |
Glypican 1 / GPC1 Recombinant Protein |
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11-327 | 0.1 mg | EUR 595.25 |
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. |
Glypican 1 / GPC1 Recombinant Protein |
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11-328 | 0.1 mg | EUR 595.25 |
Description: Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. |
CD28H / IGPR-1 Recombinant Protein |
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11-383 | 0.1 mg | EUR 595.25 |
Description: CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
PD-1 / PDCD1 Recombinant Protein |
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11-403 | 0.1 mg | EUR 542.75 |
Description: Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer. |
DNAM-1 / CD226 Recombinant Protein |
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11-431 | 0.1 mg | EUR 595.25 |
Description: DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2. |