Recombinant Human Anti-Siglec-15

Recombinant Human Anti-Siglec-15 

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Recombinant Mouse Siglec-15/CD33L3 Protein

RP01289 10μg
EUR 191.75

Recombinant Mouse Siglec-15/CD33L3 Protein

RP01290 500μg
EUR 214.5

Recombinant Cynomolgus Siglec-15/CD33L3 Protein

RP01292 10μg
EUR 191.75

Recombinant Cynomolgus Siglec-15/CD33L3 Protein

RP01294 50μg
EUR 191.75

Recombinant Human Siglec-10 Protein

RP02048 100μg
EUR 851.5

Recombinant Human Siglec-10 Protein

RP02261 10μg
EUR 308.75

Recombinant Human Siglec-10 Protein

RP02498 100μg
EUR 1706.25

Recombinant Human CD33/Siglec-3 Protein

RP00159 20 μg
EUR 219.6

Recombinant Human MAG/Siglec-4a Protein

RP00424 10 μg
EUR 219.6

Recombinant human Siglec-2/CD22 Protein

RP01199 10 μg
EUR 186

Recombinant human Siglec-9/CD329 Protein

RP01193 10 μg
EUR 276

Recombinant human Siglec-5/CD170 Protein

RP01196 20 μg
EUR 231.6

Recombinant Human Siglec-6/CD327 Protein

RP02493 500μg
EUR 234

Recombinant Human Siglec-10 Protein, His Tag

E40KMP1244 20ug
EUR 495

Recombinant Human Siglec-10 Protein, His Tag

E40KMP2152 20ug
EUR 495

Recombinant Human SIGLEC-9 Protein, Fc Tag

E40KMH1721 20ug
EUR 495

Biotinylated Recombinant Human Siglec-10 Protein

RP02499 1000μg
EUR 1423.5

Recombinant Human Siglec-8/SAF-2 Protein

RP02491 1000μg
EUR 260

Recombinant Human Siglec-8/SAF-2 Protein

RP02494 1000μg
EUR 260

Human CellExp? CD33 / SIGLEC-3, human recombinant

7370-10 each
EUR 320.4

Human CellExp? CD33 / SIGLEC-3, human recombinant

7370-50 each
EUR 861.6

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-10ug 10ug
EUR 187.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-1mg 1mg
EUR 3274.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-500ug 500ug
EUR 2312.4
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-50ug 50ug
EUR 363.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Siglec-10 Recombinant Protein

11-190 0.1 mg
EUR 714.3
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-269 0.1 mg
EUR 821.4
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-275 0.1 mg
EUR 714.3
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-278 0.1 mg
EUR 714.3
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-411 0.1 mg
EUR 714.3
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Human CellExp? Siglec-2 / CD22, Mouse Recombinant

P1330-10 each
EUR 183.6

Human CellExp? Siglec-2 / CD22, Mouse Recombinant

P1330-50 each
EUR 510

Recombinant Human Siglec-5 (C-6His-Flag-Fc)

EPT208 10ug
EUR 83.4
Description: Recombinant Human Sialic Acid-binding Ig-like Lectin 5 is produced by our Mammalian expression system and the target gene encoding Glu17-Thr434 is expressed with a 6His, Flag, Fc tag at the C-terminus.

Recombinant Human Siglec-2/CD22 Protein, His Tag

E40KMP1207 20ug
EUR 495

Recombinant Human MAG/Siglec-4a Protein, His Tag

E40KMP1608 20ug
EUR 495

Recombinant Human Siglec-2/CD22 Protein, His Tag

E40KMP1894 20ug
EUR 495

Siglec-9 Recombinant Protein

11-268 0.1 mg
EUR 714.3
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-9 Recombinant Protein

11-298 0.1 mg
EUR 714.3
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-9 Recombinant Protein

11-300 0.1 mg
EUR 714.3
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-8 Recombinant Protein

11-317 0.1 mg
EUR 714.3
Description: Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

Siglec-8 Recombinant Protein

11-319 0.1 mg
EUR 714.3
Description: Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

Siglec-3 Recombinant Protein

91-401 0.05 mg
EUR 556.8
Description: CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.

Siglec-3 Recombinant Protein

92-412 0.05 mg
EUR 651.3
Description: Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).

Biotinylated Recombinant Human Siglec-10(R119A) Protein

RP02585 100μg
EUR 1423.5

Biotinylated Recombinant Human Siglec-2/CD22 Protein

RP02496 100μg
EUR 1423.5

Recombinant Human siglec 6 Protein, Avi His Tag

E40KMP2076 20ug
EUR 495

Recombinant Human siglec 9 Protein, hFc His Tag

E40KMP2080 20ug
EUR 495

Recombinant Human siglec 8 Protein, Avi His Tag

E40KMP2084 20ug
EUR 495

Recombinant Human siglec 5 Protein, hFc His Tag

E40KMP2087 20ug
EUR 495

Recombinant Human siglec 8 Protein, hFc His Tag

E40KMP2088 20ug
EUR 495

Recombinant Human siglec 3 Protein, hFc His Tag

E40KMP2094 20ug
EUR 495

Recombinant Human Anti-Siglec-15