Recombinant Human SIGLEC-3/CD33

Recombinant Human SIGLEC-3/CD33 

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Human CellExp? CD33 / SIGLEC-3, Fc Tag, Human Recombinant

P1334-50
EUR 436

Anti-human CD33/Siglec 3 Monoclonal Antibody Unconjugated, Flow Validated

FC01508 100µg, 500µg
EUR 201
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody Unconjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD33/Siglec 3 Monoclonal Antibody APC Conjugated, Flow Validated

FC01508-APC 25 Tests, 100 Tests, 200 Tests
EUR 176
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody APC Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD33/Siglec 3 Monoclonal Antibody Biotin Conjugated, Flow Validated

FC01508-Biotin 100µg
EUR 234
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody Biotin Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD33/Siglec 3 Monoclonal Antibody FITC Conjugated, Flow Validated

FC01508-FITC 25 Tests, 100 Tests, 200 Tests
EUR 137
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody FITC Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Anti-human CD33/Siglec 3 Monoclonal Antibody PE Conjugated, Flow Validated

FC01508-PE 25 Tests, 100 Tests, 200 Tests
EUR 153
Description: Mouse Monoclonal human CD33/Siglec 3 Antibody PE Conjugated, Flow Validated. Validated in Flow Cytometry and tested in Human.

Siglec-3 Recombinant Protein

91-401 0.05 mg
EUR 464
Description: CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytoplasmic tail containing two conserved immunoreceptor tyrosine based inhibition motifs (ITIMs). Eleven human Siglecs have been characterized. Siglecs 5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions. They are collectively referred to as CD33 related Siglecs. CD33 related Siglecs have differential expression pattern within the hematopoietic system. They are involved in the regulation of cellular activation within the immune system. Siglec 3 expression is restricted to cells of myelomonocytic lineage. Siglec3 recruits SHP1 and SHP2 to its ITIMs upon phosphorylation.

Siglec-3 Recombinant Protein

92-412 0.05 mg
EUR 542.75
Description: Mouse myeloid cell surface antigen CD33(CD33) is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD33 contains one Ig-like C2-type domain and one Ig-like V-type domain. CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, CD33 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33 induces apoptosis in acute myeloid leukemia. CD33 is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML).

Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

C445-10ug 10ug
EUR 131
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.

Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

C445-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.

Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

C445-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.

Recombinant Human Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-Fc-6His)

C445-50ug 50ug
EUR 273
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM EDTA, pH 7.2.

Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)

CJ10-10ug 10ug
EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)

CJ10-1mg 1mg
EUR 2283
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)

CJ10-500ug 500ug
EUR 1613
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Mouse Sialic Acid Binding Ig-Like Lectin 3/Siglec-3/CD33 (C-6His)

CJ10-50ug 50ug
EUR 369
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-10ug 10ug
EUR 156
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-1mg 1mg
EUR 2729
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-500ug 500ug
EUR 1927
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human Sialic acid-binding Ig-like lectin 15/Siglec-15/CD33 antigen-like 3/CD33L3

CW37-50ug 50ug
EUR 303
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

CD33 Human Recombinant Protein

PROTP20138 Regular: 20ug
EUR 317
Description: CD33 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 265 amino acids (18-259 a.a) and having a molecular mass of 29.1kDa.CD33 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

CD33 Recombinant Protein (Human)

RP006340 100 ug Ask for price

Siglec-10 Recombinant Protein

11-190 0.1 mg
EUR 595.25
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-9 Recombinant Protein

11-268 0.1 mg
EUR 595.25
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-10 Recombinant Protein

11-269 0.1 mg
EUR 684.5
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-275 0.1 mg
EUR 595.25
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-10 Recombinant Protein

11-278 0.1 mg
EUR 595.25
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec-9 Recombinant Protein

11-298 0.1 mg
EUR 595.25
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-9 Recombinant Protein

11-300 0.1 mg
EUR 595.25
Description: siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains。Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.

Siglec-8 Recombinant Protein

11-317 0.1 mg
EUR 595.25
Description: Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

Siglec-8 Recombinant Protein

11-319 0.1 mg
EUR 595.25
Description: Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8. Siglec-8 was first identified by CD33 homology screening of ESTs from a cDNA library generated from a patient diagnosed with idiopathic hypereosinophilic syndrome and was originally termed SAF-2 (sialoadhesin family 2). At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Two splice variants of Siglec-8 exist. The initially characterized form contains 431 amino acid residues in total, subsequently, a longer form of Siglec-8, initially termed Siglec-8L. Both forms of Siglec-8 are found in eosinophils and contain a V-set domain with lectin activity and two C2-type Ig repeat domains in the extracellular region.

Siglec-10 Recombinant Protein

11-411 0.1 mg
EUR 595.25
Description: The siglecs (sialic acid-binding Ig-like lectins) are a distinct subset of the Ig superfamily with adhesion-molecule-like structure. We describe here a novel member of the siglec protein family that shares a similar structure including five Ig-like domains, a transmembrane domain, and a cytoplasmic tail containing two ITIM-signaling motifs. Siglec-10 was identified through database mining of an asthmatic eosinophil EST library. The Siglec-10-VAP-1 interaction seems to mediate lymphocyte adhesion to endothelium and has the potential to modify the inflammatory microenvironment via the enzymatic end products.

Siglec 9 Recombinant Protein

91-630 0.05 mg
EUR 490.25
Description: Sialic acid-binding Ig-like lectin 9(Siglec 9) is expressed by peripheral blood leukocytes (neutrophils and monocytes but not eosinophils), and found in liver, fetal liver, bone marrow, placenta, spleen and in lower levels in skeletal muscle, fetal brain and so on. It is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It also binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.

Human CellExp? Siglec-15, Human Recombinant

P1343-10
EUR 164

Human CellExp? Siglec-15, Human Recombinant

P1343-50
EUR 403

Siglec-3 Conjugated Antibody

C32577 100ul
EUR 397

Recombinant Human MMP-3 Protein

PROTP08254-3 10ug
EUR 317
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids).

Recombinant Human MAG/Siglec-4a Protein

RP00424 10 μg
EUR 183

Recombinant human Siglec-15/CD33L3 Protein

RP01187 5 μg
EUR 136

Recombinant human Siglec-9/CD329 Protein

RP01193 10 μg
EUR 230

Recombinant human Siglec-5/CD170 Protein

RP01196 20 μg
EUR 193

Recombinant human Siglec-2/CD22 Protein

RP01199 10 μg
EUR 155

Human CellExp? Siglec-15, Mouse Recombinant

P1466-10
EUR 164

Human CellExp? Siglec-15, Mouse Recombinant

P1466-50
EUR 479

Siglec-1 / CD169 Recombinant Protein

11-194 0.1 mg
EUR 595.25
Description: Alternate names for sialoadhesin include siglec-1 and CD169 (cluster of differentiation 169). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. It is defined as an I-type lectin, since it contains 17 immunoglobulin (Ig) domains (one variable domain and 16 constant domains), and thus also belongs to the immunoglobulin superfamily (IgSF). Since sialoadhesin binds sialic acids with its N-terminal IgV-domain, it is also a member of the SIGLEC family. Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells.

MAG / Siglec-4a Recombinant Protein

11-288 0.1 mg
EUR 542.75
Description: Myelin-associated glycoprotein (MAG), a nervous system cell adhesion molecule, is an I-type lectin that binds to sialylated glycoconjugates, including gangliosides bearing characteristic structural determinants. Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. In dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides.

MAG / Siglec-4a Recombinant Protein

11-289 0.1 mg
EUR 542.75
Description: Myelin-associated glycoprotein (MAG), a nervous system cell adhesion molecule, is an I-type lectin that binds to sialylated glycoconjugates, including gangliosides bearing characteristic structural determinants. Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. In dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides.

Siglec-2 / CD22 Recombinant Protein

11-455 0.1 mg
EUR 542.75
Description: B-cell receptor CD22 is also known as Sialic acid-binding Ig-like lectin 2 (Siglec-2), B-lymphocyte cell adhesion molecule (BL-CAM), T-cell surface antigen Leu-14, which belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. CD22 mediates B-cell B-cell interactions, and may be involved in the localization of B-cells in lymphoid tissues. Siglec-2 / CD22 binds sialylated glycoproteins, one of which is CD45. Siglec2 / CD22 plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.

IL-3 Interleukin-3 Human Recombinant Protein, His Tag

PROTP08700-3 Regular: 50ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 154 amino acids fragment (20-152) and having a total molecular mass of 17.3kDa and fused with a 20 aa N-terminal His tag. ;The IL3 His is purified by proprietary chromatographic techniques.

CD33 recombinant monoclonal antibody

A5158 100ul X 3
EUR 681
Description: A recombinant monoclonal antibody from rabbit against human CD33 for WB,ELISA

CD33 Recombinant Protein (Mouse)

RP122546 100 ug Ask for price

CD33 Recombinant Protein (Mouse)

RP122549 100 ug Ask for price

CD33

33A-100T 100 test
EUR 349

CD33

33B-01MG 100 test
EUR 284

CD33

33CFB-100T 100 test
EUR 388

CD33

33F-100T 100 test
EUR 297

CD33

33PE-100T 100 test
EUR 349

CD33

33PP-100T 100 test
EUR 518

CD33

33PU-01MG 0,1 mg
EUR 219

CD33

PR27318 5 ug
EUR 191

Human CellExp? Siglec-2 / CD22, Mouse Recombinant

P1330-10
EUR 153

Human CellExp? Siglec-2 / CD22, Mouse Recombinant

P1330-50
EUR 425

Human Myeloid cell surface antigen CD33 (CD33)

1-CSB-EP004925HU
  • EUR 505.00
  • EUR 265.00
  • EUR 1827.00
  • EUR 766.00
  • EUR 1218.00
  • EUR 335.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Myeloid cell surface antigen CD33(CD33),partial expressed in E.coli

Human CD33 Antibody

33418-05111 150 ug
EUR 261

PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9

PROTP49763-3 Regular: 25ug
EUR 317
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques.

TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant

PROTP10600-3 Regular: 5ug
EUR 317
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques.

Recombinant Human SIGLEC-3/CD33